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Clinical data
Trade namesAzalia, Cerazette, Desogen, Marvelon, Mercilon, Mircette, Novynette, others
AHFS/Drugs.comMicromedex Detailed Consumer Information
Pregnancy categoryUS: X (Contraindicated)
Routes of administrationBy mouth [1]
Drug classProgestin; Progestogen
ATC codeG03AC09 ( WHO )
Legal status
Legal statusUS: ℞-only
Pharmacokinetic data
Bioavailability76% (range 40–100%) [3] [4]
Protein bindingDesogestrel: 99%: [5] • Albumin: 99% Etonogestrel: 95–98%: [1] [2] • Albumin: 65–66% • SHBG: 30–32% • Free: 2–5%
MetabolismLiver, intestines (5α- and 5β-reductase, cytochrome P450 enzymes, others) [2]
Metabolites• Etonogestrel [2] [1] [3] • Others [5] [2] [3]
Elimination half-lifeDesogestrel: 1.5 hours [5] Etonogestrel: 21–38 hrs [5] [6]
ExcretionUrine: 50% [5] Feces: 35% [5]

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Active substance desogestrel
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