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Fluconazole
Clinical data
Trade namesDiflucan, Celozole, others
AHFS/Drugs.comMonograph
MedlinePlusa690002
License dataUS   FDA: fluconazole
Pregnancy categoryAU: D US: C (low dose)
Routes of administrationby mouth, IV, topical
ATC codeD01AC15 ( WHO ) J02AC01 ( WHO )
Legal status
Legal statusAU: S3 (Pharmacist only) / S4, UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability>90% (oral)
Protein binding11–12%
Metabolismliver 11%
Elimination half-life30 hours (range 20-50 hours)
Excretionkidney 61-88%

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Fluconazole, 5 reviews:

Comment №1 about product

Patients with impaired renal function will be at risk of overdose. Mammalian demethylase activity is much less sensitive to fluconazole than fungal demethylase.


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