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Danazol
Clinical data
Trade namesDanatrol, Danocrine, Danol, Danoval, others
AHFS/Drugs.comMonograph
MedlinePlusa682599
Pregnancy categoryAU: D US: X (Contraindicated)
Routes of administrationBy mouth
Drug classAndrogen; Anabolic steroid; Progestin; Progestogen; Antigonadotropin; Steroidogenesis inhibitor; Antiestrogen
ATC codeG03XA01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
BioavailabilitySaturable with dosage, higher with food intake [3]
Protein bindingTo albumin, SHBG, CBG [4] [5] [6]
MetabolismLiver (CYP3A4) [1] [2]
Metabolites• 2-OHM-Ethisterone [2] • Ethisterone [7] [8]
Elimination half-lifeAcute: 3–10 hours [1] [3] Chronic: 24–26 hours [1]
ExcretionUrine, feces [1] [3]

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